Patient-reported distress at a cancer center during the COVID-19 pandemic.

e18644 Background: Assessments of health-related quality life (HRQOL) are conducted by health systems to analyze and improve patient-centered care. Numerous studies have shown that the COVID-19 pandemic poses unique stressors for patients with cancer. However, impact on HRQOL in cancer is unknown. This study investigates change self-reported global scores before during pandemic. Methods: In this single-institution retrospective cohort study, who completed Patient-Reported Outcomes Measurement Information System (PROMIS) at a comprehensive center were identified. Surveys analyzed assess PROMIS mental (GMH) physical (GPH) different time periods (pre-COVID: 3/1/5/2019-3/15/2020, surge1: 6/17/2020-9/7/2020, valley1: 9/8/2020-11/16/2020, surge2: 11/17/2020-3/2/2021, valley2: 3/3/2021-6/15/2021). Results: A total 29,983 surveys among 7,209 included study. Mean GMH (50.57) similar various pandemic: surge1 (48.82), valley1 (48.93), surge2 (48.68), valley2 (49.19). GPH score was significantly higher pre-COVID (42.46) than (36.88), (36.90), (37.33) (37.14) (Table). During pandemic, mean (49.00) (37.37) obtained through in-person (48.53) (36.94) telehealth. Conclusions: single institution reported stable deteriorating as indicated survey. Modality survey (in-person versus telehealth) did not affect scores. [Table: see text]